"The legendary sci-fi animation, a live-action film at last."
In 2199, five years after the Gamilons began an invasion of Earth, the planet has been ravaged by the aliens' bombs. The remnants of humanity have fled underground to escape the irradiated surface. One day, former pilot Susumu Kodai discovers a capsule sent from the planet Iscandar that tells of a device that can remove the radiation from the Earth's surface. The Earth Defense Force rebuilds the battleship Yamato with a new type of propulsion system to make the 148,000 light year trip to Iscandar in hopes of saving the Earth. Within one year, the radiation will drive the rest of humanity to extinction.
Susumu Kodai

Yuki Mori

Shirō Sanada

Daisuke Shima

Hajime Saito

Mamoru Kodai

Aihara

Doctor Sado

Hikozaemon Tokugawa

Yasuo Nanbu

Saburō Katō

Akira Yamamoto

Furuya

Kenjiro Ota

Sasaki

Isaoka
Shima's wife
Heikuro Todo

Jūzō Okita

Operator
M. Nishina

Desura/Gamirasu

narrator

Segawa
Unknown Role
Unknown Role

Shimada
Unknown Role

Higashida

Tobita

Hoshino
Jiro Shima
Ando

Saito's mother

Desler (voice)

Unknown Role

Nanba

Unknown Role

Unknown Role
Unknown Role

Unknown Role
Kazuhiko Sugiyama

Sukeharu Yabu
Space cavalier
Nishio
Okita's son

young Susumu Kodai

analyzer (voice)

Unknown Role

Unknown Role

Unknown Role

Akira Nemoto
Unknown Role
Unknown Role

young Mamoru Kodai
Unknown Role
Iscandar (voice)

Inoue
Yamato crew
Honjo