Virginia, 1803. After the United States of America acquires the inmense Louisiana territory from France, a great expedition, led by William Lewis and Meriwether Clark, is sent to survey the new lands and go where no white man has gone before.
Cpt. Meriwether Lewis

Lt. William Clark

Sacajawea

Julia Hancock

Sgt. Gass

Charbonneau

Chief Cameahwait

Wild Eagle

President Thomas Jefferson

Mr. Hancock

Shoshone Woman (uncredited)

Crow Woman (uncredited)
Chief Le Borgne (uncredited)

Night Camp Sentry (uncredited)

Helmsman Cruzatte (uncredited)

Tom (uncredited)

Mrs. Martha Hancock (uncredited)
