When he was 12 years old, Bill Cody, later knew as Buffalo Bill, is rider for "pony express" carrying the mail through the wilds of America. It becomes later caravans guide. When driving one of them meets Luisa, the niece of a priest who tried to evangelize the savage tribes accompanied by a converted Indian. It is a dangerous time because, before the advancing white man, the Sioux tribes are buying weapons from unscrupulous dealers...
Buffalo Bill Cody

Wild Bill Hickok

Calamity Jane

Pastor Norman Lieberman
Ethel Lieberman

Ted

Luisa
Guillermo

Colonel Carr

Dittle

St. James

Agnes St. James

Frank North

Steve

Red Cloud
Douglas

Utter

Charlie

Señorita Mortimer
Chica de saloon
Russell

Majors
Waddell
Mortimer

Padre de Bill

Madre de Bill
Hija de Steve